Antidepressants

“Short and simple psychological programs can prevent people from relapsing when they stop their antidepressants.”

Previously taking antidepressants could make individuals less likely to respond to treatment for bipolar II depression.

A new study, published in the British Medical Journal, investigates the prevalence of off-label prescribing for antidepressant medication in primary care settings.

People diagnosed with severe depression show the same changes in brain scans when they respond to a placebo as they do when they take an actual antidepressant, according to a new study. Researchers also found that those whose symptoms were decreased by a placebo were more likely to report relief from antidepressant drugs.

Leading researchers point out that a new antidepressant study in NEJM failed to account for withdrawal symptoms, casting doubt on the results.

A new as-yet-unpublished trial of duloxetine (Cymbalta) for fibromyalgia has presented more evidence of suicidal events in teens.

In a new study, researchers found no evidence of antidepressant group variance, which means that there's no particular group of patients who improve more than others on the drug.

Use of antidepressants increased the risk of organ-specific malformations in women with depression

Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

A new study, published in JAMA Neurology, found that older people who regularly took anticholinergic drugs, including certain cold medicines or antidepressants, had poorer...

Pregnant women taking antidepressant medications, especially during the second trimester, have an increased risk of preeclampsia, a potentially serious or even fatal condition.

Researchers, Jon Jureidini, Jay Amsterdam and Leemon McHenry, have taken a closer look at the data from a randomized control trial of citalopram (Celexa) that was ghostwritten and then used by the manufacturers to support claims of the drug’s efficacy and safety in the treatment of child and adolescent depression. To get the background on this story, we connected with Dr. Leemon McHenry, an investigator in this study and a lecturer in philosophy at California State University, Northridge.

Data from the National Health and Nutrition Examination Surveys (2005-2008) show that 11% of Americans 12 and over take antidepressants. 60% of those have...

Veterans diagnosed with PTSD and taking SSRIs, novel antidepressants, or atypical antipsychotics are more likely to develop dementia.

Researchers from McMaster University's Department of Medicine, presenting at this year's American Society for Bone and Mineral Research's annual meeting, found that the magnitude...

Pneumonia cases in the elderly are strongly associated with use of anticholinergic medications, including benzodiazepines and tricyclic antidepressants.

Researchers compared the efficacy of antidepressants using different rating scales and found them to be no different—just slightly better than placebo, and not meeting the criteria for clinical significance.

A new study suggests that taking antidepressants impairs empathy, while the experience of depression itself does not.

Researchers from Vanderbilt University and the University of Alabama found, in a retrospective study of increased suicidal behavior among 36,842 children who were new...

Trials of antidepressants for relapse prevention are confounded by withdrawal effects caused by the drugs.

Adhering to a commonly prescribed medication for ADHD in children is associated with higher chances of being prescribed antidepressants in adolescence.

The more that patients feel that they have a high-quality relationship with their prescribing physician, the more likely that they will regard their own responses to antidepressants as positive.

A study comparing the effects on cognition of major depression (MDD) vs. SSRIs finds that healthy subjects learn significantly better from positive feedback than...

Taking an SSRI antidepressant was associated with a 26% increased risk of violent crime conviction.

Study reveals most patients are dissatisfied with prescribers' support when discontinuing antidepressants.